Pericytes a new target for the treatment of central nervous system lesions
| Reference number | |
| Coordinator | Karolinska institutet - Institutionen för cell- och molekylärbiologi |
| Funding from Vinnova | SEK 10 500 |
| Project duration | July 2013 - August 2013 |
| Status | Completed |
Purpose and goal
The purpose for this planning grant was for the collaborating partners, Dr. Göritz at the Karolinska Institute and M. Orre from the Netherlands Institute for Neuroscience, to meet discuss and plan a project, for which they will apply for the ´VINNMER Marie Curie Incoming grant. The ultimate aim of these meetings was to shape and write a project plan and a grant application for the ´VINNMER Marie Curie Incoming grant´. This has now succeeded and an application has been written that will be sent to VINNOVA before the 17 September 2013.
Results and expected effects
This planning project resulted in a well-defined project plan and a grant application for the project ´Pericytes a new target for the treatment of multiple sclerosis lesions´ that aims to determine whether a specific type of pericytes are responsible for the scar formation in an mouse model for Multiple sclerosis (MS) and if modulation of these cells will improve the function and disease etiology. It also aims to elucidate the molecular mechanisms underlying pericyte-derived scar formation and validate the findings in human post-mortem MS tissue from the Netherlands Brain Bank.
Approach and implementation
The project leader for the proposed project ´Pericytes a new target for the treatment of multiple sclerosis lesions´, M. Orre, visited the Karolinska Institute for a week to discuss and plan the project and to finalize the application for the `VINNMER Marie Curie incoming grant´ with a deadline September 17, 2013, this was successful since a grant application and a project plan has been written.