Training lung immune function to prevent tuberculosis
| Reference number | |
| Coordinator | Linköpings universitet - Institutionen för klinisk och experimentell medicin |
| Funding from Vinnova | SEK 238 748 |
| Project duration | October 2016 - January 2018 |
| Status | Completed |
| Venture | Personal mobility between societal sectors |
Important results from the project
The purpose of the project was that the project coordinator would be able to interact closely with the company, ISAB. More specifically, the PreciseInhale method was to be adapted to fit mice lungs in order to study how lungs can be strengthened in the immune defense against Mycobacterium tuberculosis.
Expected long term effects
The project coordinator has been trained at the company to perform exposures and measurements with the PreciseInhale instrument. In this process, the existing rat equiplent has been evaluated in order to identify necessary modificaiton for mouse studies. The time plan of the project couldn´t be kept and therefore, mouse studies are prepared but not initiated. However, the projet coordinator has together with the company sumitted an EU proposal within Horizon 2020 iFunding is sought to perform an international study for which the present project forms the fundament.
Approach and implementation
More specifically: A ventilator that simulates mouse breathing has been purchased and tested. Software has been developed for measurement of breathing frequency and dosage for mouse lungs. The project coordinator has performed a course in lab animal science to gain admitance to performing animal studies. An application for ethical approval for initiation of the planned experiments was submitted and approved. All these preparations are very important for the planned EU project.