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Rapid Non-invasive prenatal testing (NIPT) via digital counting of fetal DNA

Reference number
Funding from Vinnova SEK 1 000 000
Project duration June 2017 - June 2018
Status Completed

Important results from the project

Our goal was to develop a fast, inexpensive and safe fetal test for chromosomal aberrations based on unique technology detecting circulating DNA in blood. The technology has been optimized and proven to work on blood samples and with standard equipment available in many laboratories. Researchers in bioinformatics have designed a data script for probe design that identifies target sequences in DNA.

Expected long term effects

The molecular technology is optimized in a model system and is also tested on blood samples. The method can be used for fetal testing but also for patient follow up and therapy selection for cancer treatment. The bioinformatic script for probe design can also be applied to other technologies that require advanced, large-scale probe design.

Approach and implementation

Olink Bioscience has developed and optimized the molecular technology. Researchers in bioinformatics from Uppsala University have developed the data script to find target sequences in the genome. Olink Bioscience has also further developed the business plan and has been initiated collaboration with instrument manufacturers, end users, clinicians, regulatory expertise and IP advisors to define market opportunities.

The project description has been provided by the project members themselves and the text has not been looked at by our editors.

Last updated 25 November 2019

Reference number 2017-01441

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