Multimodal visualization of the microcirculation during treatment of critical limb ischemia

Purpose and goal

The project had two main goals - to develop a prototype of a microcirculatory camera that can measure blood flow and oxygen saturation, and to evaluate the technology for its potential to be used in the treatment of patients with chronic limb threatining ischemia. The development included algorithms, electronics, mechanics, and software. The clinical studies have involved measurements on patients before, during, and after endovascular intervention. With the extension of the project, both goals have been met satisfactorily with a working prototype and promising clinical results.

Expected results and effects

The project has generated a prototype and clinical results that help the company expand its product portfolio with an attractive microcirculatory combination camera, which contributes to increased sustainable growth and strengthened international competitiveness. The clinical findings indicate that the technology can be an important tool for treatment planning and follow-up of patients with chronic limb threatening ischemia and provide the necessary feedback to the surgeon during intervention. In the long run, this can lead to more efficient healthcare and improved health.

Planned approach and implementation

The project partners Perimed AB, the Department of biomedical engineering at Linköping University, and the Vascular Surgery Clinic, have had clear areas of responsibility and expertise, which has been a crucial factor for success. The parties have also been able to work tight together because the project leader at the company has been an adjunct lecturer at the University, and the technical researchers have had walking distance to the clinic. Both developing and using the technology in parallel has been a challenge but has worked thanks to an early prototype for data collection.