Development of a sensor enabling a new clinical method for continuous cardiac output monitoring during surgery
|Coordinator||KUNGLIGA TEKNISKA HÖGSKOLAN - Skolan för elektro- och systemteknik|
|Funding from Vinnova||SEK 1 961 776|
|Project duration||September 2016 - May 2019|
Purpose and goal
We have compared the capnodynamic method to existing methods and created a prototype sensor chip for CO2 measurements in patient’s breath under surgery.
Expected results and effects
The capnodynamic method showed good agreement and trending capacity with the reference method in high risk surgery patients. The sensor has demonstrated detection of CO2 concentrations down to 0.5% at a time resolution of 27 ms.
Planned approach and implementation
The project consisted of three work-packages: WP1: “Specification, communication and business plan”, WP2: “Integrated combined gas and flow sensor”, and W P3: “Clinical evaluation of the capnodynamic method”. WP1 was implemented by common brainstorming sessions, WP2 through prototype manufacturing in the KTH cleanroom and characterization in KTH analyses laboratories, and WP3 through clinical trials at KS. This approach has worked well.