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Development of a sensor enabling a new clinical method for continuous cardiac output monitoring during surgery

Reference number
Coordinator KUNGLIGA TEKNISKA HÖGSKOLAN - Skolan för elektro- och systemteknik
Funding from Vinnova SEK 1 961 776
Project duration September 2016 - May 2019
Status Completed

Purpose and goal

We have compared the capnodynamic method to existing methods and created a prototype sensor chip for CO2 measurements in patient’s breath under surgery.

Expected results and effects

The capnodynamic method showed good agreement and trending capacity with the reference method in high risk surgery patients. The sensor has demonstrated detection of CO2 concentrations down to 0.5% at a time resolution of 27 ms.

Planned approach and implementation

The project consisted of three work-packages: WP1: “Specification, communication and business plan”, WP2: “Integrated combined gas and flow sensor”, and W P3: “Clinical evaluation of the capnodynamic method”. WP1 was implemented by common brainstorming sessions, WP2 through prototype manufacturing in the KTH cleanroom and characterization in KTH analyses laboratories, and WP3 through clinical trials at KS. This approach has worked well.

The project description has been provided by the project members themselves and the text has not been looked at by our editors.

Last updated 8 January 2019

Reference number 2016-02328

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