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Development and manufacture of bioceramic powders for use in nerve regeneration

Reference number
Coordinator BIOARCTIC AB
Funding from Vinnova SEK 2 000 000
Project duration October 2014 - December 2017
Status Completed

Purpose and goal

The aim of the project has been to develop a stable process for the preparation of calcium sulfate hemihydrate of clinical quality for the production of biodegradable implants, for treatment of complete spinal cord injury. During the implementation of the project, two primary methods have been evaluated for material production and a promising process for manufacturing has been developed. The specification for material and final implant is high, and some process optimization remains.

Expected effects and result

The results of the project have been buildup up knowledge around calcium sulfate and processes for phase transformation into castable materials for clinical use. A promising manufacturing method has been developed and critical parameters for material properties have been identified and optimized. Expected effects of the project are further development of the manufacturing process to achieve the full material specification, followed by process verification and validation.

Planned approach and implementation

The project arrangement was ambitious but well established with the various project partners. The major challenge of the project has been the development of a process for producing materials with very specific characteristics. Process development in the project claimed more resources than planned, and since subsequent development required pre-developed materials, not all original work packages could be carried out. Unfortunately, all available skills in the project could thus not been fully utilized.

The project description has been provided by the project members themselves and the text has not been looked at by our editors.

Last updated 30 January 2019

Reference number 2014-03403

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