Controlled and treatment of opiate-requiring pain using biosensors.
| Reference number | |
| Coordinator | Sensidose AB - Sensidose Aktiebolag |
| Funding from Vinnova | SEK 1 228 500 |
| Project duration | March 2019 - September 2022 |
| Status | Completed |
Purpose and goal
The aim was to examine if physiological data (skin conductance/electrodermal activity (EDA), heart rate (HR) and blood volume pulse (BVP), skin temperature (ST), and movement) correlate with subjective pain (as measured by recordings on a VAS scale). Objective pain measurement could be developed as a tool control and manage pain treatment in the future.
Expected results and effects
Two clinical experiments were performed, on healthy volunteers and on patients during mobilization following othopedic surgery. While the results on the healthy volunteers were promising, data from the orthopedic patients indicates that capturing pain by physiological measurements using biosensors is challenging.
Planned approach and implementation
Data wes collected in two open clinical studies, a pre-study with healthy volunteers and a main study with patients after orthopedic surgery. For the main study, a wearable sensor recorded physiological data (skin conductance/electrodermal activity (EDA), heart rate (HR) and blood volume pulse (BVP), skin temperature (ST), and movement) continuously. Pain intensity was recorded on a visual analogue scale (VAS). A custom software was written that calculated quantitative summaries (features): 17 from the EDA , 17 from BVP, 12 from HR, and 12 features from ST .