Important results from the project
The overall aim was to improve the use for companies of synchotron radiation to study lung diseases. As a consequence, we showcased nano X-Ray Fluorescence (nano-XRF) as an effective tool for companies. Trulylabs participated on site and scanned for two days at NanoMAX (a hard nano probe beamline at MAX IV Laboratories). Additionally, the team helped to develop a graphical use interface (GUI) for nano-XRF image analysis.
Expected long term effects
In the long term, the project is expected to make nano-XRF more systematically usable for companies and other users through continued validation of the GUI. The tool can reduce post-beamtime bottlenecks, support rapid hypothesis generation from elemental maps, and streamline data interpretation. The project is also expected to contribute to correlative workflows where nano-XRF is combined with multiplexed immunofluorescence and O-PTIR on biological tissue sections.
Approach and implementation
The project was implemented in stages, focusing on user input, sample preparation, nano-XRF measurements, data analysis and interpretation. The activities were well aligned with the goals and the project developed mainly as planned. Some parts, especially the interpretation of the latest results, remain partially completed. The collaboration with Trulylabs, CIPA and MAX IV worked well and contributed to new workflows, a public GUI and continued development.
The project description has been provided by the project members themselves and the text has not been looked at by our editors.