Rare cell analysis of heterogeneous samples in breast cancer research
| Reference number | |
| Coordinator | Göteborgs Universitet - Institutionen för biomedicin, Avdelningen för patologi |
| Funding from Vinnova | SEK 48 180 |
| Project duration | December 2013 - March 2014 |
| Status | Completed |
Important results from the project
The purpose of this project was to drive breast cancer diagnostics towards personalized medicine. We have defined the role of the applicant in the project, and how the project and collaborating partners can promote the applicant´s career. We have outlined project details with focus on the applicant and possible long-term effects for the applicant and all partners. Finally, we have submitted a complete application to VINNMER Marie Curie Incoming grant.
Expected long term effects
Our project will combine current cutting-edge technologies such as in vivo enrichment for circulating tumor cells with sophisticated single cell analysis. Our approach will allow us to assess the feasibility of applying different biomarker panels for enumerating and characterizing circulating tumor cells from breast cancer patients. In the long term, this approach will be used beyond breast cancer samples to drive personalized medicine towards clinical application. The planning grant allowed the applicant with partner to develop the project and to write a complete application.
Approach and implementation
Our project will launch in late summer 2014, starting on the isolation and labeling procedures using breast cancer cell line cell spiked into peripheral blood. In parallel and with increasing focus we will adapt and develop down-stream applications including single-cell analysis. The applicant has visited the Swedish host twice to initiate, develop and finalize the application. The visits included meetings with collaborating academic and industrial partners as well as checking private issues associated by moving the entire family.