Protein design for receptor mediated passage of the bloodbrain barrier

Important results from the project

The planning grant was intended to establish international, innovative, interdisciplinary research at the interface of protein engineering, biochemistry, and biomedicine. The long-term challenge of the proposed project is to build protein-based carriers that are able to penetrate the blood-brain barrier and deliver therapeutics for more efficient treatment of neurological disorders.

Expected long term effects

By visiting universities in Sweden and in the USA I have established a collaboration, built a realistic time-plan, and determined the methods and resources necessary to carry out the proposed research. I have submitted a full application for VINNMER Marie Curie Incoming.

Approach and implementation

To carry out the planning of the project I have visited University of Washington (David Baker) and Linnaeus University (Department of chemistry and biomedicine) and secured the financing for the portion of the ´Marie Curie incoming´ not covered by VINNOVA. This will potentially establish a close collaboration between involved institutions.