From Continuous Glucose Monitoring to Continous Glucose Microneedle Monitoring for efficient diabetes treatment

Purpose and goal

This project aimed at developing a new minimal invasive sensor for glucose monitoring based on painless microneedles earlier developed by the partners. As compared to state-of-the-art technology, microneedle-based glucose measurements offer painless monitoring without the need of blood samples. This project aim was successfully fulfilled.

Expected results and effects

The concept has been evaluated in trials and proven to work. This has led to that the technology has been patented and that further development between the project partners will take place. The work has thus far resulted in a peer-review conference article and a journal article.

Planned approach and implementation

The project was divided into eight work packages, of which the Swedish parties participated in five of them. In the initial phases, requirements specifications were set up and the design was conceptualized. This was followed by a larger work package where a miniaturized enzyme-based glucose sensor was developed from scratch. In the next work package, sensor technology was integrated with microneedles to create a full system. In parallel ways to bring the system into product and design concepts was investigated. Finally, the system was verified in-vivo.