Development and formulation centre for next generation biologics
| Reference number | |
| Coordinator | RISE Research Institutes of Sweden AB - Biovetenskap och material, STOCKHOLM |
| Funding from Vinnova | SEK 36 000 000 |
| Project duration | January 2020 - December 2024 |
| Status | Ongoing |
| Venture | Center for biologics |
Important results from the project
Mapping of excipients effects on protein stability, as the effects of surfactants, preservatives, surfaces and drying techniques. Three new platforms for stable encapsulation and enteral delivery of sensitive components. At CoSAXS, MAX IV, an automated SAXS environment has been established, and advanced analysis methods have been further developed. Courses in science, GMP and IP have been arranged. New collaborations and expanded training programs strengthen the supply of expertise in biologics.
Expected long term effects
NBF has created a strong network between academia, institutes and industry in biologics and is a platform for new collaborations. Young researchers have been trained in the formulation of biologics, thereby strengthening the industry. New formulation concepts, characterization methods and service offerings provide the conditions for new innovations and products. New national and international projects have been created in new constellations with NBF as a base.
Approach and implementation
NBF has 4 scientific WPs and 3 supporting WPs. PhD students, post-docs and researchers collaborated closely thanks to the agreement that creates a center that is open internally, but closed externally. Materials from industry are shared with the entire center. The research program has been continuously developed, adding new projects. The collaboration has worked very well. Changes in partners have occurred, which have been handled in collaboration. A hub was investigated but not started.