CSF-1 as a target of lupus
| Reference number | |
| Coordinator | Göteborgs Universitet - Institutionen för medicin |
| Funding from Vinnova | SEK 13 194 |
| Project duration | March 2011 - December 2011 |
| Status | Completed |
Purpose and goal
The aim of the planning grant is to establish collaboration between Harvard Medical School and Göteborg University (GU). The project combines molecular basic science incl. unique mouse models with clinical expertice and the possibility of human studies. The scientific aim is to pin down the mechanism of sunlight induced autoimmune skin disease. The role of macrophages and dendritic cells (the most common cell types of the skin) and Colony Stimulating Factor-1 (CSF-1), the principle macrophage growth factor, will be elucidated.